mouse

Scientists Just Genetically Edited a Million Years of Evolution Into Mouse DNA

Scientists Just Genetically Edited a Million Years of Evolution Into Mouse DNA

Changing the number of chromosomes in an animal can take millions of generations to happen in nature through the course of evolution – and now, scientists have been able to make these same changes in lab mice in a relative blink of an eye. The new technique using stem cells and gene editing is a …

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synthetic mouse embryo pictured next to natural embryo

Lab-made mouse embryos grew brains and beating hearts, just like the real thing

Scientists coaxed mouse stem cells to grow into synthetic embryos that began developing hearts and brains, just like the real thing. The lab-made embryos, crafted without any eggs or sperm and incubated in a device that resembles a fast-spinning Ferris wheel full of tiny glass vials, survived for 8.5 days. That’s nearly half the length …

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Scientists use stem cells to create synthetic mouse embryos

Scientists use stem cells to create synthetic mouse embryos

Scientists have created “synthetic” mouse embryos from stem cells without a father’s sperm or a mother’s egg or womb. The lab-created embryos mirror a natural mouse embryo up to 8 ½ days after fertilization, containing the same structures, including one like a beating heart. In the near term, researchers hope to use these so-called embryoids …

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Mouse embryos grown without eggs or sperm: why and what's next?

Mouse embryos grown without eggs or sperm: why and what’s next?

Natural and synthetic mouse embryos grown by developmental biologist Magdalena Zernicka-Goetz’s research group.Credit: Gianluca Amadei, Charlotte Handford The recipe for mammalian life is simple: take an egg, add sperm and wait. But two new papers demonstrate that there is another way. Under the right conditions, stem cells can divide and self-organize into an embryo on …

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UK Scientists Create a Mouse Embryo From Stem Cells, No Sperm or Egg Required

UK Scientists Create a Mouse Embryo From Stem Cells, No Sperm or Egg Required

A comparison of a natural (top) and synthetic (bottom) mouse embryo, which shows similar brain and heart formation. Photo: Amadei and Handford Scientists in the UK say they’ve pulled off a feat of genetic engineering: creating a “synthetic” mouse embryo without the need for egg or sperm cells. The embryos were created with stem cells …

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Scientists create synthetic mouse embryos, a potential key to healing humans

Scientists create synthetic mouse embryos, a potential key to healing humans

Comment on this story Comment Stem cell researchers in Israel have created synthetic mouse embryos without using a sperm or egg, then grown them in an artificial womb for eight days, a development that opens a window into a fascinating, potentially fraught realm of science that could one day be used to create replacement organs …

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